EMERGING APPLICATIONS OF EXTRACELLULAR VESICLES IN TUMOR THERAPY

Emerging applications of extracellular vesicles in tumor therapy

Abstract Extracellular vesicles (EVs) have tremendous potential as nano/micron-sized drug delivery carriers.Their physical, chemical and biological characteristics distinguish them as unique carriers with specific pharmacokinetic, circulating metabolic, and biodistribution patterns in the delivery of therapeutic cargoes.They are critical mediators

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Proline Metabolism in Tumor Growth and Metastatic Progression

Cancer cells show a formidable capacity to survive under stringent conditions, to elude mechanisms of control, such as apoptosis, and to resist therapy.Cancer cells reprogram their metabolism to support uncontrolled proliferation and metastatic progression.Phenotypic and functional heterogeneity are hallmarks of cancer cells, which endow them with

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